Search results for "Yeast genome"

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CYGD: the Comprehensive Yeast Genome Database.

2005

The comprehensive resource is available under http://mips.gsf.de/genre/proj/yeast/.; International audience; The Comprehensive Yeast Genome Database (CYGD) compiles a comprehensive data resource for information on the cellular functions of the yeast Saccharomyces cerevisiae and related species, chosen as the best understood model organism for eukaryotes. The database serves as a common resource generated by a European consortium, going beyond the provision of sequence information and functional annotations on individual genes and proteins. In addition, it provides information on the physical and functional interactions among proteins as well as other genetic elements. These cellular network…

ved/biology.organism_classification_rank.speciesSACCHAROMYCES CEREVISIAE GENOME;COMPREHENSIVE YEAST GENOME DATABASE;CYGD;PROTEIN INTERACTION;EUROPEAN CONSORTIUM;SEQUENCE INFORMATION;YEAST GENOME;SEQUENCED EUKARYOTIC GENOMEcomputer.software_genreGenomeSaccharomycesUser-Computer InterfaceSequence Analysis ProteinDatabases GeneticYEAST GENOME[INFO.INFO-BI] Computer Science [cs]/Bioinformatics [q-bio.QM]0303 health sciences[SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]biologyDatabase030302 biochemistry & molecular biologyEUROPEAN CONSORTIUMArticlesGenomicsCYGD[SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]PROTEIN INTERACTIONSEQUENCED EUKARYOTIC GENOMEnucleic acidsCOMPREHENSIVE YEAST GENOME DATABASEBio-informatiqueGenome FungalSEQUENCE INFORMATIONSaccharomyces cerevisiae ProteinsBioinformaticsSaccharomyces cerevisiae610Saccharomyces cerevisiaeGenètica molecularSACCHAROMYCES CEREVISIAE GENOMESaccharomyces03 medical and health sciencesAnnotationGeneticsSIMAPModel organismGene030304 developmental biologyBinding Sitesved/biologyMembrane ProteinsMembrane Transport Proteinsbiology.organism_classificationYeast[INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM]computerSDV:BIBSTranscription Factors
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The roles of whole-genome and small-scale duplications in the functional specialization of Saccharomyces cerevisiae genes

2013

Researchers have long been enthralled with the idea that gene duplication can generate novel functions, crediting this process with great evolutionary importance. Empirical data shows that whole-genome duplications (WGDs) are more likely to be retained than small-scale duplications (SSDs), though their relative contribution to the functional fate of duplicates remains unexplored. Using the map of genetic interactions and the re-sequencing of 27 Saccharomyces cerevisiae genomes evolving for 2,200 generations we show that SSD-duplicates lead to neo-functionalization while WGD-duplicates partition ancestral functions. This conclusion is supported by: (a) SSD-duplicates establish more genetic i…

0106 biological sciencesCancer ResearchGenome evolutionlcsh:QH426-470ArabidopsisSaccharomyces cerevisiaeBiology01 natural sciencesGenomeDivergenceEvolution Molecular03 medical and health sciencesMolecular evolutionPhylogeneticsGene DuplicationGene duplicationGeneticsMads-Box genesBiologyMolecular BiologyGenePhylogenyGenetics (clinical)Ecology Evolution Behavior and Systematics030304 developmental biologySmall-scale duplicationsGeneticsEvolutionary BiologyEvolutionary Theory0303 health sciencesAdaptive conflictHuman evolutionary geneticsNull mutationsSaccharomyces cerevisiae genomeProtein-Protein interactionslcsh:GeneticsEvolutionary biologyDiversificationEpistasisMolecular evolutionWhole-genome duplicationsGenome FungalYeast genomeInteractions revealResearch Article010606 plant biology & botany
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